Soochow University

Epigenetic silencing of FCGR2A by promoter hypermethylation exacerbates cardiac remodeling in post-myocardial infarction heart failure

Post-myocardial infarction heart failure (post-MI HF) is among the cardiovascular diseases with the highest morbidity and mortality rates worldwide. However, the epigenetic landscape of post-MI HF remains incompletely characterized. Here reduced representation bisulfite sequencin...

Beyond the efficiency trap: Regional AI exposure, AI knowledge, and the asymmetric governance of data-driven value propositions

Artificial intelligence (AI) is reshaping corporate strategy, yet how regional AI exposure (RAE), the intensity of local industry peers' AI inventive activities, shapes firms' data-driven value propositions (DDVPs) remains unclear. Using panel data on Chinese listed firms from 20...

Surface Vibrotactile Texture Feedback: A Scoping Review of Perceptual Evidence, Rendering Strategies, and Evaluation Practices

Surface vibrotactile texture feedback is an important HCI modality for conveying material-related information and supporting multisensory interaction. However, evidence across perception, rendering, actuation, parameter mapping, and evaluation remains fragmented. This scoping rev...

Density of Triple Coincidences in the Simple Length Spectrum of One-holed Tori

We prove that, in the Teichmüller space of one-holed tori with any fixed boundary length, including the cuspidal case, marked hyperbolic one-holed tori with three distinct simple closed geodesics of equal length form a dense, meager subset. This answers a suspicion of McShane and...

Cohn Trace Polynomials: Root Localization, Strict Log-Concavity, and Rearrangement Inequalities

We study the one-variable trace polynomials obtained from words in the rank-two free group by the Cohn normalization. We prove that every nontrivial word has all its zeros in a fixed sector about the negative real axis; after the marking involution, this is equivalently a transla...

Density of Triple Coincidences in the Simple Length Spectrum of One-holed Tori

We prove that, in the Teichmüller space of one-holed tori with any fixed boundary length, including the cuspidal case, marked hyperbolic one-holed tori with three distinct simple closed geodesics of equal length form a dense, meager subset. This answers a suspicion of McShane and...

Ultrafast Polymerization within Crowded Droplets: A Platform Based on Macromolecular Crowding and Complex Coacervation

Abstract Biomolecular condensates are coacervates formed by liquid–liquid phase separation and organized for autocatalytic biochemistry. Nevertheless, coacervate autocatalysis remains largely unexplored. Herein, we present a model droplet system to provide fresh insights into the...

Highly Polarized Narrow Linewidth Near-Infrared Emission from InSe-Based Light-Emitting Diodes

Abstract Near-infrared (NIR) light-emitting diodes (LEDs) operating beyond 900 nm are critical for biomedical imaging and optical communications. However, achieving spectrally narrow emission with controlled polarization remains challenging. This work demonstrates electrically pu...

Atomically Precise Synthesis of Carbon-Based Quantum Magnets on Inert Surfaces

Abstract Carbon-based quantum magnets (CBQMs) with tunable π-electron magnetism represent a frontier in quantum science, which are distinguished by their exceptional spin properties and structural diversity. On-surface synthesis has been indispensable for atomically precise engin...

Assessing Urban Sustainable Competitiveness and Happiness From the Perspective of Socio‐Economic Environment

ABSTRACT This study examines the sustainable competitiveness of Taiwan's 22 counties and cities between 2016 and 2020. We develop and apply a parallel dynamic two‐stage slacks‐based measure data envelopment analysis framework that integrates Shannon entropy to measure sustainabil...

Microsphere System Coloading Type I Collagen and Dexamethasone Sodium Phosphate for Osteoarthritis Therapy

Abstract Knee osteoarthritis (KOA) has no effective nonsurgical treatment. Intra-articular therapy constitutes an effective localized intervention; however, persistent lymphatic drainage and synovial vascular exchange lead to rapid drug elimination. Encapsulating bioactive agents...

Data-Driven and Quantum-Chemical Insights into Emergence of Multiresonance Effect in Thermally Activated Delayed Fluorescence Emitters

Abstract Multiresonance thermally activated delayed fluorescence (MR-TADF) emitters enable narrow-bandwidth emission and high efficiency in organic light-emitting diodes; however, the fundamental origin of the multiresonance effect remains incompletely understood. Herein, a fine-...

Screening Lithium-Ion Conductors Based on Local and Global Topology

Abstract The discovery of high-performance solid-state electrolytes remains a critical challenge for all-solid-state Li-ion batteries. To accelerate the identification of novel Li-ion conductors, we developed a hierarchical screening framework combining local structure order para...

Porous Core-Shell Tin-Based Carbon Nanofiber Networks as Free-Standing Anodes toward Advanced Lithium-Ion Batteries

Abstract Tin-based composites represent appealing anode alternatives for high-energy lithium-ion batteries because of their ultrahigh specific capacity, abundant reserves, and eco-friendly characteristics. However, their severe volume variation, electrode pulverization, and struc...

Public Database Leakage Distorts Model Rankings in Real-Spectra NMR Structure Elucidation

Abstract Sequence models that translate NMR spectra into molecular structures report up to 96% top-1 accuracy, but they are pretrained on simulated spectra and tested on public databases that can overlap those corpora. We build a leakage-controlled benchmark on nmrshiftdb2 and fi...

Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in elderly patients undergoing non-cardiac and non-neurosurgical procedures: protocol for a multicentre, double-blind, randomized, controlled trial

BACKGROUND: Whether ephedrine, when used to maintain intraoperative blood pressure, is superior to phenylephrine in reducing postoperative delirium remains uncertain. This study aims to determine whether the intraoperative management of hypotension with ephedrine, compared with p...

Gut microbiota functional remodeling and butyrate depletion amplify anti-Ro/La antibody-driven type I interferon activation in neonatal lupus

The early-life gut microbiome may influence susceptibility to antibody-mediated neonatal autoimmunity, but the underlying mechanisms remain poorly understood. We investigated whether gut microbial functional capacity and metabolites influence autoantibody-dependent immune activat...

Controlling Dual Reflection Bands of Cholesteric Liquid Crystal Polymer Network Films via Photoisomerization and Polymerization-Induced Molecular Migration

Abstract Cholesteric liquid crystal polymer network (CLCN) films featuring dual reflection bands have emerged as promising materials for decorative and anticounterfeiting applications, owing to their unique composite structural colors. Currently, these films are commonly fabricat...

Optimal scheduling of electric arc furnaces with multiple flexible resources

Under the "dual-carbon" goals, the green transition of the steel industry is crucial. The electric arc furnace (EAF), with its scrap recycling benefits, is key—yet its volatile load challenges grid stability. This study proposes a smart grid coordinated dispatch model incorporati...

Carnosol Accelerates Pressure Ulcer Healing via Keap1-Nrf2/HO-1-Mediated Mitochondrial Quality Control

Abstract Pressure ulcer pathogenesis involves ischemia-reperfusion-induced oxidative stress and mitochondrial dysfunction. Carnosol, a rosemary-derived diterpene with antioxidant properties, was investigated for its therapeutic potential in tissue repair. Carnosol pretreatment pr...