Sohag University

Upcycling PET Waste into Novel Bis-1,3,4-Oxadiazole Scaffolds as Promising Anti-Inflammatory Agents: Synthesis, Biological Evaluation, and Molecular Docking

Abstract Upcycling polyethylene terephthalate (PET) waste into high-value intermediates offers a sustainable approach to reducing plastic pollution and dependence on fossil-derived feedstocks. Here, terephthalic acid recovered from PET waste was used as a sustainable building blo...

Enhancing biodegradation of polycyclic aromatic hydrocarbons using bacterial consortia and biofilm

Abstract The release of petroleum and its constituents, such as polycyclic aromatic hydrocarbons (PAHs), into the environment poses a significant global threat due to their toxic, genotoxic, mutagenic, and/or carcinogenic properties. Using indigenous PAH-degrading bacteria to dec...

A machine learning approach to predict treatment response in myofascial pain patients receiving masseter trigger point injections

BACKGROUND: Trigger point injection (TPI) therapy is widely used for masseter myofascial pain syndrome (MPS), yet outcomes vary substantially. Individualized prediction tools are lacking, often leading to trial-and-error treatment selection. OBJECTIVE: To develop, externally vali...

Thoracotomy versus thoracoscopy in repair of esophageal atresia, prospective comparative study

Abstract Background Pediatric esophageal atresia management has come a long way in recent years. Early diagnosis and better neonatal ICU and anesthesia have contributed to a steady decline in infant mortality. Aim of the study The present study aims to compare the outcome of thor...

Integrated machine learning forecasting and grey wolf optimization for optimal operation of virtual power plants in smart distribution networks

The increasing penetration of distributed energy resources (DERs) necessitates intelligent coordination strategies that simultaneously enhance the technical, economic, and environmental performance of modern distribution networks. This paper proposes an integrated Virtual Power P...

Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction

ABSTRACT Background Chronic ankle instability and chronic low back pain are highly prevalent in musculoskeletal conditions. Emerging evidence suggests that they are interconnected through shared biomechanical, neuromuscular, and neurophysiological mechanisms, where deficits in pr...

Agent Aptness Framework (AAF 1.0): A Task-Specific Framework for Evaluating Agent-Task Correspondence

The Agent Aptness Framework (AAF 1.0) provides a task-specific method for evaluating the degree of correspondence between an agent’s demonstrated characteristics and the stated requirements of a particular assignment. AAF distinguishes agent capability from agent–task aptness and...

CD38 Inhibition Enhances FXR Signaling in Male Rats With Diabetic Steatohepatitis Through SIRT1‐Dependent Suppression of NLRP3

ABSTRACT Diabetic steatohepatitis, now clinically framed within metabolic dysfunction‐associated steatohepatitis (MASH), features progressive disruption of hepatic microarchitecture alongside sterile inflammatory microdomains. Farnesoid X receptor (FXR) activity is restrained by...

Sustainable Microcystin Removal from Water Using Low-Cost Agricultural Waste Materials

Cyanobacterial blooms are an increasing global concern due to the release of microcystins (MCs), potent hepatotoxins that threaten aquatic ecosystems, livestock, and human health. This study investigated the efficiency of low-cost natural adsorbents—rice straw (R), corn straw (C)...