Sociedad Española de Medicina de Familia y Comunitaria

The narrowing sex gap in lip and oral cavity cancer incidence in Spain: Thirty years of divergent age-period-cohort trends

Background Lip and oral cavity cancer (LOCC) accounts for a significant proportion of the overall burden of head and neck cancers, yet long-term sex-specific trends remain unclear. This study aimed to analyse sex-specific LOCC incidence trends in Spain from 1994 to 2023. Methods...

Cost-effectiveness of lenacapavir versus tenofovir disoproxil fumarate plus emtricitabine for pre-exposure prophylaxis to prevent HIV-1 transmission in gay, bisexual, and other men who have sex with men in Spain

Background Lenacapavir (LEN), a twice-yearly subcutaneous capsid inhibitor, has demonstrated superior efficacy over daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as HIV pre-exposure prophylaxis (PrEP) in clinical trials. No European cost-effectiveness analyses...