SNUH SMG-SNU Boramae Medical Center

Stiffness-Dependent Mechanotransductive Signaling in Silicone Implant-Associated Fibrotic Encapsulation

Abstract Fibrotic encapsulation remains a major limitation of silicone-based soft-tissue implants and contributes to capsular contracture. Although biochemical and immunological factors have been extensively investigated, the contribution of implant stiffness to the peri-implant...

Preoperative Thrombocytopenia Increases In-Hospital Burden but Not Postoperative Adverse Events After Total Knee Arthroplasty

Background/Objectives: Thrombocytopenia increases bleeding tendency and may complicate perioperative management in total knee arthroplasty (TKA), yet data on both in-hospital burden and post-discharge adverse events are limited. This study evaluated the association between preope...

Optimizing perioperative systemic dexamethasone use in total knee arthroplasty: a narrative review on current evidence

Abstract Background Perioperative corticosteroids, particularly dexamethasone, have become a widely adopted component of multimodal pain management in total knee arthroplasty (TKA). While clinical practice guidelines strongly recommend their use, detailed guidance on optimal dosi...