Slovak Medical University

Retinal Recombination: A robust augmentation and synthesis of retinal images with annotation fusion

Medical image synthesis has become a crucial research topic for enhancing image analysis software. The relatively small size of available datasets, the lack of ground-truth annotations, and the poor quality of registered images are among the driving reasons for the development of...

Mandibular Distraction Osteogenesis for Upper Airway Obstruction in Infants and Neonates: Airway Outcomes, Hospitalization Burden and Procedure Application in the Polish Population

Objectives: This study retrospectively evaluated the respiratory outcomes and hospitalization burden of infants and neonates diagnosed with upper airway obstruction who underwent bilateral mandibular distraction osteogenesis in the Polish population. Methods: The study analyzed 4...

The Fiscal Consequences Attributed to Multiple Myeloma in Slovakia: There is No Small Disease

Abstract Background The incidence of multiple myeloma (MM) is rising in ageing populations. New therapies have improved survival but are among the most expensive in oncology. The consequences of MM for government revenues and expenditures in Slovakia have not been quantified. Met...

Timing and trajectory of acute kidney injury predict mortality in alcohol-associated hepatitis: A multinational cohort study.

BACKGROUND: Acute kidney injury (AKI) is common in alcohol-associated hepatitis (AH) and associated with poor outcomes, yet the prognostic implications of AKI timing and early renal trajectory remain unclear. METHODS: In this prospective multicenter cohort from the Global AlcHep...

Musculoskeletal pain in healthcare workers in Slovakia: a nationwide cross-sectional observational study

The main objective of our study is to examine the prevalence of musculoskeletal pain among healthcare workers in Slovakia. The cross-sectional study analyzed a sample of 801 healthcare professionals, including physiotherapists, nurses, paramedics, and medical doctors. Data collec...

Cerebral Small Vessel Disease and Sleep-Disordered Breathing in Patients with Acute Intracerebral Haemorrhage: A Prospective Two-Centre Observational Study

Abstract Background Intracerebral haemorrhage (ICH) is the second most common stroke subtype and carries high mortality and disability. Cerebral small vessel disease (cSVD) and sleep-disordered breathing (SDB) are mechanistically linked and both implicated in ICH pathogenesis, ye...

Successful Surgical Repair of a Window Ductus and Ventricular Septal Defect in a Neonate Utilizing Preoperative Three-Dimensional Modeling

Window ductus (WD) is a very rare and anatomically distinct variant of patent ductus arteriosus, also known as a type B patent ductus arteriosus. We report the case of a neonate who was born with a rare triad of congenital heart defects including a large WD, multiple ventricular...

Enzyme-Detergent and Detergent-Detergent Protocols for Human Urethra Decellularization: A Histological and Ultrastructural Study

Abstract Background and Objectives Decellularization of the human urethra produces extracellular matrix (ECM) bioscaffolds with strong potential for reconstructive urology, yet no standardized protocols exist for either cell removal or scaffold characterization. Histological asse...