Sixth Affiliated Hospital of Xinjiang Medical University

Sequential Meridian Based Acupuncture Combined With Standard Rehabilitation After Surgery for Severe Cubital Tunnel Syndrome

Objective: To evaluate the efficacy of sequential meridian-based acupuncture combined with standard rehabilitation in patients after surgery for severe cubital tunnel syndrome (CuTS). Methods: In this prospective randomized controlled trial, 40 patients with severe CuTS who under...

Moldavoside ameliorates hypertension and autoantibodies targeting the angiotensin II type 1 receptor-induced endothelial damage via regulation of RhoE/CAV-1/eNOS axis

Globally, more than 100 million patients with resistant hypertension experience severe endothelial damage. Therefore, exploring the mechanisms underlying endothelial damage and developing effective interventions is urgently required. The clinical data and biochemical indicators o...

Comparison of efficacy and safety between unilateral biportal endoscopy and percutaneous endoscopic surgery for cervical spondylotic radiculopathy based on current evidence: a systematic review and meta-analysis

A systematic comparison of the clinical efficacy and safety between Unilateral Biportal Endoscopy (UBE) and Percutaneous Endoscopy (PE) in the Treatment of Cervical Spondylotic Radiculopathy (CSR). Computerized searches were conducted in PubMed, Cochrane Library, Web of Science,...

WEM-Mamba: a Wavelet-Enhanced MedMamba framework for rotator cuff tear classification in X-ray images

Rotator cuff tear is a common cause of shoulder pain and functional impairment, and its accurate identification is of great significance for clinical treatment decisions. Magnetic Resonance Imaging (MRI) is generally regarded as the important imaging modality for evaluating soft...

Identification and mechanistic study of metabolic-immune subtypes in COPD based on integrated transcriptomic-metabolomic analysis

This study aimed to characterize immune cell metabolic alterations and their regulatory mechanisms in chronic obstructive pulmonary disease (COPD), and to identify metabolism-related immune subtypes associated with lung dysfunction to support immunometabolic classification and ta...

Phage anti-defense genes targeting NAD + metabolism and DNA replication are associated with a broad host range against Klebsiella pneumoniae

. Deletion of these genes collapsed the host spectrum from 109 strains to fewer than 10, significantly compromising antibacterial efficacy. The wild-type phage substantially improves survival in a mouse bacteremia model. Our study identifies candidate genetic factors associated w...

Qufeng Zhijing Capsule attenuates airway inflammation in experimental asthma and is associated with c-Myc/YTHDF1/TRPV1-related signaling

Background Qufeng Zhijing Capsule (QFZJ) is a traditional Chinese medicine formulation used for asthma-related respiratory symptoms, but its effects on airway epithelial inflammation and the underlying molecular mechanisms remain unclear. Methods OVA-induced asthmatic rats receiv...