Sixth Affiliated Hospital of Kunming Medical University

Dynamic association between gut microbiota succession and host metabolism: differential effects of antibiotic intervention duration on glucose and lipid metabolism in high-fat diet-induced obese mice

Abstract Background The gut microbiota plays a critical role in the onset and progression of obesity. Previous studies have indicated that antibiotic administration may influence host physiology and pathology by modulating the gut microbiota. However, whether different durations...

Acupuncture alleviates the progression of lumbar disc herniation by regulating the autophagy level of nucleus pulposus cells through the SIRT1/Sestrin2 pathway.

BACKGROUND AND PURPOSE: Lumbar disc herniation (LDH) is a degenerative spine disease and the most common cause of lower back pain, with a high prevalence in younger patients. The use of acupuncture (AC) as a conservative treatment for LDH has received widespread attention at home...