Singapore Immunology Network

Cutaneous IgG4 ‐Related Disease Accompanied by Granulomatous Vasculitis: A Case Report

ABSTRACT IgG4‐related disease (IgG4‐RD) is a systemic fibroinflammatory disorder characterized by dense infiltration of IgG4‐positive plasma cells, fibrosis, and elevated serum IgG4 levels. Although various cutaneous manifestations of IgG4‐RD have been described, and vasculitic c...

Distinct migratory dendritic cell subsets cooperate to prime tissue-resident memory-like CD8⁺ T cells in mouse tumors

Tumor-infiltrating tissue-resident memory (TRM)-like CD8+ T cells correlate with positive prognosis and better responses to cancer immunotherapy, yet the mechanisms underlying their specification remain ill-understood. Here, we use the KP (KrasG12D, p53-/-) mouse model of lung ad...