Singapore General Hospital

P1.042. Utility of a Fenestrated Surgical Drain for the Prevention and Treatment of Esophageal Leak

Abstract Topic Benign Disease: Iatrogenic Esophageal Disease, Perforation and Postsurgical Complications Background Esophageal transmural defects are associated with high morbidity and mortality. Sponge-based endoscopic vacuum therapy (EVT) is effective but costly and requires fr...

The digital native fallacy: how age-based assumptions exclude young adults with chronic disease from digital health innovations

Digital health interventions often rely on a “digital native” assumption of inherent user competence and stable access. Drawing on US-based evidence, we challenge this: social media fluency does not equate to health literacy 1 , digital access is structurally unstable 2 , and ins...

Early evaluation of the WCT EVI MAP project: implementation, challenges, and emerging impact on evidence-based tumour classification

<ns5:p>Background The WHO Classification of Tumours (WCT) underpins cancer diagnosis globally, but the evidence-base used to inform tumour classification has never been systematically appraised. The WCT EVI MAP project was designed to address this need by developing a structured,...

How I Teach ICU Triage: A Three-Column Framework for Premorbid, Morbid, and Postmorbid Assessment

Abstract Intensive care unit (ICU) triage is a cognitively complex and emotionally charged task that challenges clinicians across training levels. Although trainees may recognise prognostic factors and ethical principles, many lack a coherent structure to integrate these elements...

Evaluating large language model performance in US FDA regulatory science

Abstract Background Clinical and population decision-making relies on the systematic evaluation of extensive regulatory evidence. The FDA drug reviews provide detailed information on clinical trial design, enrollment criteria, sample size, randomization, comparators, endpoints, a...

Characterisation of liver disease using quantitative MRI: report of the imaging arm of the ELEGANCE study

Evolving disease aetiology and rising prevalence of chronic liver disease are driving an increase in hepatocellular carcinoma (HCC). Non-contrast quantitative MRI (qMRI) has shown promising capability for characterising liver health and risk of liver related outcomes, but has not...

Erector spinae plane block in bariatric surgery: a systematic review and meta-analysis of randomized controlled trials with trial sequence analysis

The use of erector spinae plane (ESP) block has been reported to decrease opioid requirements for patients undergoing bariatric and metabolic surgeries (BMS). We aim to systematically review and examine the evidence for the use of ESP block in BMS. MEDLINE, Embase, Scopus, and CE...

Risk of new‐incident mental health diagnoses following SARS ‐ CoV ‐2 infection amongst children and young adults in Singapore: a retrospective cohort study

Background Mental‐health‐disorders in children/young adults increased post‐pandemic; however, the absence of linkage to COVID‐19 registries made direct attribution of psychological sequelae to acute infection challenging. Methods Healthcare‐claims databases in Singapore were util...

Effect of medial opening wedge high tibial osteotomy versus unicompartmental knee arthroplasty on mental health: a comparative study with propensity score-matched analysis

INTRODUCTION: Medial opening wedge high tibial osteotomy (MOWHTO) and unicompartmental knee arthroplasty (UKA) are established treatments for knee osteoarthritis (KOA). This study compared their effects on mental health outcomes. METHODS: A retrospective cohort study was conducte...