Sinai University

Predictive correlations and mechanical assessment of asphalt mixtures modified by sasobit redux and crumb rubber

Abstract To satisfy advanced pavement design methodologies such as the Mechanistic-Empirical Pavement Design Guide (MEPDG), accurate characterization of asphalt mixtures through parameters like the dynamic modulus│E*│is critical. However, obtaining these parameters via advanced l...

The Senescent Heart’s Hidden Drain: Senescence-Associated Secretory Phenotype–Mediated Cardiac Lymphatic Dysfunction as a Novel Mechanistic Axis in Heart Failure With Preserved Ejection Fraction: A Narrative Review

Heart failure with preserved ejection fraction (HFpEF) represents the dominant and most therapeutically recalcitrant phenotype of heart failure in the contemporary era, yet its pathophysiology remains incompletely delineated. This narrative review advances a novel mechanistic fra...