Simon Fraser University

Drone as First Responder (DFR): A Short Report on a DFR Program in an American Police Agency

Abstract Police agencies are increasingly incorporating drones into their policing operations. Very recently, some police agencies have begun to use drones as a form of first responder: deploying drones to calls for police service on first instance and without specific solicitati...

In the wake of extreme heat: equitable urban heat planning for residential buildings

Extreme heat is invisible, deadly, and its threat is shaped through dominant approaches of urban planning and development. In this study we asked ‘how is equity considered within cities' responses to extreme heat for residential buildings'. Using the City of Burnaby as a case stu...

Joint economic and epidemiological modelling of alternative pandemic response strategies

Abstract In an emerging pandemic, policymakers need to make decisions with limited information and require trade-offs between the health impact of the pandemic and the economic costs of the response. Most mathematical models have focused on direct health impacts, neglecting the e...

Optimizing culture-free approaches to recover high-quality Mycobacterium tuberculosis genomic variation

Background. Mycobacterium tuberculosis ( Mtb ) genomic epidemiology often relies on culturing patient sputum, a time- and labour-intensive process. Hybrid capture approaches have been successfully used to enrich Mtb DNA from complex clinical samples, yet the accuracy of variant i...

A systematic review of early neuroimaging and neurophysiological biomarkers for post-stroke mobility prognostication

Abstract Background Accurate prognostication of mobility outcomes is essential to guide rehabilitation and manage patient expectations. The prognostic utility of neuroimaging and neurophysiological biomarkers remains uncertain when measured early post-stroke. This systematic revi...

Development and validation of an amyloid PET dementia of the Alzheimer's type (DAT) score

Background Alzheimer's disease (AD) can be debilitating if left untreated, but its progression may be altered through early detection. Objective To develop and evaluate a convolutional neural network (CNN) for detecting AD from amyloid PET brain images and to investigate the regi...

Platform ecosystem governance and its influence on the process of formation and institutionalization of new practices for development

This study examined how platform ecosystem governance mechanisms, as enacted through human intermediaries, influenced the formation and institutionalization of new practices among smallholder farmers in an ICT4D context. We conceptualize platform ecosystems as socio-technical sys...

Design of a New 3-UPU/S Parallel Ankle Rehabilitation Mechanism

Ankle injuries may lead to severe complications, including chronic instability and reduced mobility. Rehabilitation therefore plays a critical role in restoring normal ankle function and preventing long-term impairment. However, conventional manual physiotherapy presents several...

Alcohol exposure induces reversible nucleolar amyloidogenesis

The nucleolus is a dynamic membraneless organelle that rapidly responds to cellular perturbations. Under harsh environmental conditions, it transitions from a ribosome biogenesis center into a dense proteinaceous structure, known as a nucleolar amyloid body (A-body). Although A-b...

Cannabis sativa and the endocannabinoid system in cervical cancer: molecular targets and mechanistic insights from preclinical models-narrative review

Abstract Introduction Cervical cancer is among the major causes of cancer-related mortality, particularly in low- and middle-income countries where access to effective screening and treatment is limited. The endocannabinoid system (ECS), which comprises of cannabinoid receptors (...

Eruption source parameters for a Canadian mafic explosive eruption: an example from Sii Aks (Tseax) volcano

Abstract Observations from tephra fall deposits are needed to constrain input parameters used to model tephra fall hazard, but this is challenging for mafic Canadian volcanoes, which are often in remote locations. Here, we present eruption source parameters (ESPs) for the approxi...

From Reflection to Resurgence: Co-Researching Through Storymaking and Truthtelling With Urban Indigenous Women

In the context of a community–university partnership, we reflect on the co-development of a research process centred on urban Indigenous women’s leadership, cultural resurgence, and collective well-being. Together, Indigenous and university-based co-researchers created spaces for...