Silpakorn University

Beyond the Needle: Transforming Traditional Healthcare with Microneedle Drug Delivery Systems

In the present era, modern drug delivery systems play a fundamental role in ensuring the systematic delivery of the drug into the body, reaching the desired targets. Across recent decades, the drug delivery system has evolved from simple oral and injectable formulations to interp...

Potent Caspase‐1 Antagonists From Dihydropyridine Derivatives: In Vitro Fluorescence Assays and Cell Imaging

Caspase‐1 is a key marker in pyroptosis and inflammation, playing a central role in the pathogenesis of various acute and chronic inflammatory diseases. While some caspase‐1 sensing and inhibition studies have been reported, the use of DHPs for these applications remains unexplor...

Convergence Rates of Levenberg–Marquardt Regularization Under General Source Conditions

We investigate the convergence of the Levenberg–Marquardt (LM) iterative regularization method for linear ill-posed inverse problems in Hilbert spaces under general source conditions characterized by admissible index functions. We introduce admissibility conditions tailored to th...

Development of Aqueous Two-Phase System for Eco-Friendly and Decolorized Triterpenoids Extraction of Centella asiatica Optimized by Response Surface Methodology

Centella asiatica (L.) Urban extracts are widely used in food, cosmetic, and pharmaceutical products. Conventional solvent extraction requires organic solvents and often produces dark green extracts due to chlorophyll co-extraction, limiting their industrial applications. This st...

The role of King Chitrasen (Mahendravarman) in the expansion of the Chenla Kingdom: A study of inscriptions and historical geography

This study explores the military campaigns of King Chitrasen, later known as King Mahendravarman, and his role in expanding the Chenla Kingdom through a geographical analysis of ancient inscriptions and the Least Cost Path (LCP) methodology. By integrating GIS-based LCP analysis,...

Do positive psychological capabilities, self-directed learning, and adaptability influence hospitality employability readiness among Thai elderly?

As Thailand becomes an aging society, older adults represent an important potential workforce for the tourism and hospitality industry. However, limited research has explained how positive psychological capabilities, self-directed learning skills, and adaptability skills jointly...