Sigmovir Biosystems (United States)

Geometric Derivation of the Yang–Mills Mass Gap from the Static 12³ Tessellation in Geometric Topology 14D (TG): Resolution of the Clay Problem, Proton Radius Puzzle and Multiple ΛCDM Tensions

We derive the Yang–Mills mass gap geometrically from the static 12×12×12 tessellation of the General Theory (TG): Δ_QCD = (P_s P_d / 12) m₂ ≃ 1.478 GeV (0.3σ agreement with experimental glueball data). The same discrete systolic architecture (so(12) ⊕ so(7) ⊕ so(7) → so(26)) reso...

HMGB1-targeted anti-inflammatory rBox A gene therapy for viral airway infections and systemic inflammatory disease models

High mobility group box 1 (HMGB1) is a host-derived proinflammatory molecule released during cell injury. Elevated extracellular HMGB1 levels have been associated with disease severity. HMGB1 contributes to host influenza responses by stimulating TLR4/MD-2 signaling, amplifying l...