Sidney Kimmel Cancer Center

A novel perioperative pathway for hip fractures in the older adult: a pre-post quality improvement study using statistical process control

Despite advances in medical care, the incidence of medical complications, especially delirium, remains high in patients with hip fracture. Although individual components of hip fracture pathways have been studied, the components together have not. At a tertiary academic medical c...

Perioperative Durvalumab for Resectable NSCLC : Updated Outcomes for Japanese Patients in AEGEAN

ABSTRACT In the phase 3 AEGEAN study, perioperative durvalumab plus neoadjuvant chemotherapy significantly improved the primary endpoints of event‐free survival (EFS) and pathological complete response (pCR) in patients with resectable NSCLC versus neoadjuvant chemotherapy alone....

Examining the Associations of Altered Metabolism in Black Women with Endometrial Cancer

Abstract Metabolic syndrome is a modifiable risk factor in endometrial cancer patients and is predictive of disease outcomes in endometrial cancer survivors. While metabolic syndrome has been on the rise in the United States, there is also a concerning, disproportionate increase...

Three-dimensional chromatin architecture is rapidly restored after DNA replication

Studies of post-replicative chromatin exclusively focus on the kinetics of protein binding after DNA replication to understand maintenance of transcriptional programs. Here we investigated both chromatin-bound factors and the three-dimensional architecture of the post-replicative...