Siddhartha University

Rational Coformer Screening of Multicomponent Crystals of Abiraterone Acetate Using Machine Learning (ML) and Multicomponent Hydrogen Bond Propensity (MCHBP): A Comprehensive Structural and Computational Investigation

Abstract Multicomponent crystalline systems offer a viable approach to improving the physicochemical and pharmacokinetic properties of drugs, thereby enabling the rational optimization of solid forms through coformer identification. The conventional process relies on empirical kn...

Artificial intelligence modelling of cobalt chromite (CoCr 2 O 4 ) nanofluid flow over a curved surface with melting phenomena and nonlinear thermal radiation

This research looks at the incompressible flow of a cobalt chromite nanoparticle mixed with water and ethylene glycol in a 50:50 ratio, passing through a Darcy–Forchheimer porous medium with a curved stretching surface embedded in it. Included in the model are four typically hand...