Sichuan Center for Disease Control and Prevention

Safety and satisfaction of voluntary medical male circumcision among men who have sex with men in China

PURPOSE: To investigate the safety and satisfaction of circumcision among men who have sex with men (MSM), as voluntary male medical circumcision (VMMC) may be an innovative and acceptable tool for HIV prevention among this population in the future. METHODS: Participants who volu...

Population genomics reveals multi-scale mechanisms sustaining schistosomiasis re-emergence in a near-elimination setting

Abstract In China, sustained snail control, environmental management, and mass drug administration with praziquantel reduced schistosomiasis to near-elimination levels, yet re-emergence in Sichuan Province during the early 2000s exposed vulnerabilities in late-stage control. We c...

HIV-tuberculosis co-infection in Liangshan, a resource-limited region of Southwest China: trends and implications in the context of integrated prevention, 2019–2024

Abstract Background Tuberculosis (TB) and HIV co-infection remains a major public health challenge in resource-limited settings. Liangshan Yi Autonomous Prefecture in Southwest China bears a dual high burden of HIV and TB. This study aimed to analyze the epidemiological trends of...

Climate change reshapes the potential transmission risk of human alveolar and cystic echinococcosis in western China: a projection based on MaxEnt models

BACKGROUND: Echinococcosis, a severe zoonotic parasitic disease, imposes a significant health burden in western China, primarily as alveolar (AE) and cystic (CE) forms caused by Echinococcus multilocularis (Em) and E. granulosus sensu lato (Egsl), respectively. Its transmission,...

Impact of pig farming activities on the gut microbiome and resistome of farmers: insights from metagenomics and Escherichia coli genomics

Intensive swine production entails high antimicrobial use and close human–animal microbial exchange, with potential to remodel the human gut ecosystem and promote cross-host antimicrobial resistance (AMR) transmission. To quantify the impact of occupational exposure on the human...

Prevalence of Keshan disease at the township level in China: a cross-sectional study

Keshan disease (KD), an endemic myocardiopathy with unclear etiology, lacks primary preventive measures. This study aimed to assess the prevalence of KD at the township level using spatial epidemiology, elucidate its distribution characteristics for further precision classificati...

Local genetic distance-guided qPCR method for genotyping canine/feline coronaviruses

Canine coronavirus (CCoV) and feline coronavirus (FCoV) are highly infectious in companion animals. Nevertheless, due to genomic recombination and mutagenesis of the two CoVs, these difficulties dampen their precise diagnosis especially by genotypes. Herein, we addressed these pr...