Sichuan Academy of Traditional Chinese Medicine

Finite element analysis of a novel repair device for lumbar spondylolysis

Abstract Background This study aimed to compare the biomechanical differences between a novel repair device for lumbar spondylolysis and a nail–hook internal fixation system through three-dimensional finite element analysis. Methods Three-dimensional images of L4–S1 were construc...

Exposure-informed lung transcriptomic analysis links predicted NNK targets to cell type-specific remodeling programs in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is associated with cigarette smoking, yet the relationship between the tobacco-specific nitrosamine nicotine-derived nitrosamine ketone (NNK) and IPF-associated lung transcriptional remodeling remains incompletely understood. Here, we developed...