Shizuoka Medical Center

Disease‐Specific Ventricular Unloading Responses to Impella Support Revealed by Three‐Dimensional Pressure‐Volume‐Flow Landscape Analysis

ABSTRACT Background Impella support alters left ventricular pressure‐volume (PV) relations, but disease‐specific unloading responses across the full support range remain incompletely characterized. We developed a three‐dimensional pressure‐volume‐flow landscape (3D‐PVL) framework...

Balancing Circulatory Support and Ventricular Unloading in Post‐Infarction Ventricular Septal Perforation: A Computational Analysis of ECPELLA Support Configurations

BACKGROUND: Ventricular septal perforation (VSP) is a catastrophic complication of acute myocardial infarction frequently associated with cardiogenic shock. Combined venoarterial extracorporeal membrane oxygenation (VA-ECMO) and Impella support (ECPELLA) has emerged as a promisin...