Shifa International Hospital

Ghost (virtual) ileostomy compared with protective ileostomy after low anterior resection for rectal cancer: A GRADE-assessed systematic review and meta-analysis

Protective ileostomy is commonly performed after low anterior resection for rectal cancer to mitigate the clinical consequences of anastomotic leakage; however, it is associated with stoma-related and reversal-related morbidity. Ghost ileostomy has emerged as a selective alternat...

Blinatumomab versus chemotherapy in pediatric B-ALL: A meta-analysis of randomized trials in relapsed and high-risk frontline disease

BACKGROUND: B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer, comprising almost 25 % of childhood malignancies. Despite advances in chemotherapy, relapse remains a major cause of treatment failure, particularly in high-risk patients. Blinatumomab, a...