Shenzhen Center for Disease Control and Prevention

Engineered exosome MDC@Ex-γ3-CeO₂@PDA for multi-target therapy of sepsis-induced acute lung injury

Sepsis-induced acute lung injury (ALI), with a complex pathogenesis, currently lacks clinically effective multi-target therapeutic strategies. Musca domestica cecropin (MDC), a promising antimicrobial, anti-inflammatory, and endothelial-repairing peptide, is limited by its high m...

Group Climate Questionnaire as a Referent-Shift Consensus Measure: Actor-Partner Interdependence Modeling

This study examined the Group Climate Questionnaire-Short Form (GCQ-S) as a referent-shift consensus measure of cohesion among 83 Chinese undergraduates in 15 positive psychology-informed psychoeducational groups over 14 weekly sessions. Using multisample actor-partner interdepen...

Trajectories of memory function before and after cardiovascular disease among hypertensive patients

The trajectories of cognitive function before and after cardiovascular disease (CVD) have been widely explored in the general population, but less is known in hypertensive patients who are regarded as the most vulnerable patients for both CVD and dementia. The cohort study was co...

Lysine pyruvylation: decoding the molecular language of pyruvate signaling

Lysine pyruvylation (Kpy) converts pyruvate availability into a reversible protein modification, placing a central carbon metabolite directly within cellular regulatory circuits. An initial study identified STAT1 K201 pyruvylation and showed that this modification suppresses type...

Safety and satisfaction of voluntary medical male circumcision among men who have sex with men in China

PURPOSE: To investigate the safety and satisfaction of circumcision among men who have sex with men (MSM), as voluntary male medical circumcision (VMMC) may be an innovative and acceptable tool for HIV prevention among this population in the future. METHODS: Participants who volu...

UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron loss, skeletal muscle atrophy, paralysis, and eventually death. Mitochondrial dysfunction plays a pivotal role in ALS pathogenesis, although the precise pathogenic mechani...

Associations Between Residential Indoor Environmental Indicators and Respiratory Allergic Symptoms Among Children in Shenzhen, China

Children are vulnerable to indoor environmental exposures, yet evidence from direct measurements in residential environments remains limited. This study included 115 observations from 74 children in Shenzhen during 2023–2024, with 111 observations available for regression-based a...

Digitally enabled GP-specialist collaborative care helped improve hypertension outcomes and reduced hospital referrals in China

As China deepens health system reform to strengthen primary care by integrating hospital-based specialist services into community settings, empirical evidence is still limited. This quasi-experimental difference-in-differences analysis examined the effect of the digitally enabled...

Spatial-seasonal distribution and ecological risk assessment of multiple herbicides (chloroacetamides, triazines, chlorophenoxy acids, bentazone) and their transformation products in the Yangtze River, China

Abstract Herbicides such as chloroacetamides, chlorophenoxy acids, triazines, and bentazone are widely used in agriculture, contaminating aquatic ecosystems. However, their distribution and ecological risks in the Yangtze River are not clear. Thus, we analyzed 144 surface water s...

Unlocking bipolar electrode-electrolyte solid-solid conversion in aqueous zinc-halogen batteries for high Zn utilization across various cell formats

The increasing demand for high-energy-density batteries pushes practical aqueous Zn-based batteries. However, high Zn utilization achieved in coin symmetric cells is unable to translate to full cells, especially large pouch cells, due to the poor reversibility of Zn and capacity...