Shenzhen Bao'an District People's Hospital

Associations of Anatomical Location and Reader Experience With the Diagnostic Performance of Multiparametric MRI ‐Derived VI ‐ RADS for Muscle Invasive Bladder Cancer: A Multicenter Multireader Study

ABSTRACT Background The associations of tumor location and reader experience with Vesical Imaging‐Reporting and Data System (VI‐RADS) performance remain unclear. Purpose To evaluate the associations of tumor location and reader experience with VI‐RADS performance in detecting mus...

Association of the Dietary Inflammatory Index with bone mineral density and osteoporosis among adults with type 2 diabetes

Dietary inflammatory load, quantified using the Dietary Inflammatory Index (DII), reflects pro-inflammatory dietary patterns that may contribute to impaired bone health. However, population-based evidence regarding the association between dietary inflammatory potential and bone m...

Short-term neonatal in-hospital associations following delivery room ETI versus PPV resuscitation: a multicenter retrospective cohort study

Abstract Background Endotracheal intubation (ETI) and positive pressure ventilation (PPV) are core neonatal resuscitation interventions. Baseline clinical imbalances confound gestational-age (GA)-specific associations between ETI and in-hospital adverse events. We evaluated GA-st...

Clinical outcomes and molecular features of CEBPA-mutated MPAL: a multi-center case series

Mixed phenotype acute leukemia (MPAL) is rare and aggressive, with no standard therapy. CEBPA mutations define favorable-risk AML, but their significance in MPAL is unknown. We reviewed eight CEBPA -mutated MPAL patients from five Chinese centers. Four received allo-HSCT in first...

Targeting PRMT5 alleviates diabetic cardiomyopathy: mechanisms involve Ndufs2 R118 dimethylation-mediated complex I protection and serum PRMT5 as a biomarker

Abstract Background Diabetic cardiomyopathy (DCM) is defined by progressive cardiac dysfunction driven by myocardial ATP depletion, where mitochondrial electron transport chain (ETC) Complex I dysfunction acts as a critical factor. Protein arginine methyltransferase 5 (PRMT5) mai...

Tibial cortex transverse transport accelerates diabetic wound healing via systemic mobilization of non-classical monocytes

Aims: To clarify the immunomodulatory mechanisms by which tibial cortex transverse transport (TTT) accelerates wound healing in a type 2 diabetic rat model, with particular focus on the dynamics of subsets of monocytes and macrophages. Methods: A total of 186 male Sprague-Dawley...