Sheffield Children's NHS Foundation Trust

Mapping the Evidence for Allied Health Interventions for Preterm Infants With Feeding Aversion: A Scoping Review

AIMS: To identify and map the evidence on allied health professional led interventions for preterm infants with feeding aversion, and to critically examine the literature to inform clinical practice and highlight research gaps. METHODS: A Joanna Briggs Institute scoping review wa...

Lithium chloride in vitro treatment shows potential to rescue the neuronal phenotype caused by WDFY3 haploinsufficiency

We provide a comprehensive phenotypic characterization of loss-of-function (LoF) variants in WDFY3 based on the largest cohort reported to date (n = 32). Our findings define a monogenic disorder marked by neuropsychiatric features (including autism and ADHD), mild to moderate neu...

Service evaluation project: a journey through dementia distress management

Purpose Care home (CH) residents with dementia may exhibit distressed behaviours due to unmet needs, with non-pharmacological interventions being the first line intervention. This study aims to evaluate the efficiency of the Distressed Behaviour Pathway (DBP), delivered to care h...