Shaoxing Second Hospital

Effectiveness and Safety of Fixed‐Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real‐World Study From China

BACKGROUND: This study assessed the real-world effectiveness and safety of a fixed-dose combination (FDC) of metformin and empagliflozin in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This prospective, multicenter, real-world study enrolled consecutive patient...

Clinical value of artificial intelligence computer-aided diagnosis system in lymph node ultrasonography

This article explores the clinical value of the artificial intelligence computer-aided diagnosis system in the diagnosis of superficial lymph nodes. In this study, characteristic ultrasonic parameters of 185 cases of lymph nodes (including 110 benign and 75 malignant) confirmed b...

Evaluation of bone fracture risk among men with prostate cancer treated with androgen receptor pathway inhibitor-containing therapies: a systematic review and meta-analysis

Androgen receptor pathway inhibitors (ARPIs) are widely used across multiple prostate cancer disease states, but fracture outcomes are inconsistently reported across randomized trials. We aimed to quantify the risks of all-grade and grade ≥ 3 trial-reported fracture-related adver...

Baseline cardiac biomarkers and inflammatory indices for new-onset ECG abnormalities and survival in patients receiving immune checkpoint inhibitors: a single-center exploratory study

Routine inflammatory and cardiac biomarkers may help risk-stratify patients receiving immune checkpoint inhibitors (ICIs). The ECG monitoring endpoint and oncologic survival outcomes are distinct. We examined whether baseline cardiac biomarkers were associated with adjudicated ne...

Neutropenia events with androgen receptor pathway inhibitor-containing versus control therapies in prostate cancer patients: a systematic review and meta-analysis

To systematically evaluate the risk of neutropenia associated with androgen receptor pathway inhibitor (ARPI) intensification in patients with prostate cancer across phase 3 randomized controlled trials. This systematic review and meta-analysis was conducted in accordance with PR...

A multimodal Vision-Mamba model based on non-contrast CT hematoma and shell features predicts early hematoma expansion in hypertensive intracerebral hemorrhage: a multicenter study

To develop and evaluate a multimodal Vision-Mamba deep learning (DL) model integrating clinical data, noncontrast computed tomography (NCCT) hematoma features, and shell features to predict early hematoma expansion (EHE) in hypertensive intracerebral hemorrhage (HICH). In this mu...