Shantou University Medical College

A clinico-radiomic nomogram for preoperative prediction of guideline-defined indications for postoperative adjuvant therapy in early-stage cervical cancer

To develop and validate an integrated clinico-radiomic nomogram for the preoperative prediction of guideline-defined indications for postoperative adjuvant therapy in patients with FIGO stage IB–IIA cervical cancer. A total of 200 patients who underwent radical hysterectomy were...

FHL3 Regulates Vascular Smooth Muscle Cell Phenotypic Switching Through the MRTFB-SRF Signaling Axis

Genome-wide association studies have uncovered many coronary artery disease (CAD) loci, but mechanisms linking risk variants to vascular biology remain unclear. We screen candidate causal CAD genes for regulators of the vascular smooth muscle cell (VSMC) contractile phenotype usi...

Development and evaluation of a novel experimental autoimmune prostatitis model induced by a prostate-specific antigen mixture in rats

Objective To develop a novel experimental autoimmune prostatitis (EAP) model in rats using a prostate-specific antigen (PSA) mixture and to determine the optimal dose by evaluating the dose-dependent effects. Methods Male SD rats were divided into control (saline), low-dose (0.1...

Comparative efficacy and toxicity of two versus three induction chemotherapy cycles in locally advanced nasopharyngeal carcinoma: a propensity score matching analysis

Abstract Background For patients with locally advanced nasopharyngeal carcinoma (LA-NPC), the optimal number of cycles of induction chemotherapy (IC) remains uncertain. This study aimed to assess the efficiency and toxicity of different cycles of IC in LA-NPC patients. Methods Th...