Shanghai Veterinary Research Institute

Self-assembling trivalent nanoparticle vaccine enables multivalent antigen display and potent cross-protection against fowl adenovirus serotypes 4, 8b, and 11

Hepatitis-hydropericardium syndrome, caused by fowl adenovirus serotype 4(FAdV-4), and inclusion body hepatitis, caused by fowl adenovirus 8b and 11 (FAdV-8b and FAdV-11), have become widespread in China, resulting in substantial economic losses. Vaccination remains one of the mo...