Institution
Shanghai Cell Therapy Research Institute
CNnonprofit
Recent research
- Health & MedicineOpen access
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
ABSTRACT Antibody junctional diversity in jawed vertebrates arose from RAG transposon domestication, generating CDR3‐focused V(D)J recombination with lymphocyte specificity—a constrained system limiting engineered antibody diversity. To overcome these limitations, we developed AR...