Shandong Sport University

An evaluated gait-driven finite element framework for transfemoral limb–socket interface biomechanics and socket design evaluation

Abstract Background Residual limb–socket interface mechanics are central to transfemoral prosthetic comfort and stability, but their dependence on socket material, regional pressure loading, interfacial slip ( δ slip ), and interfacial friction ( µ ) remains insufficiently quanti...

The Role of Glucose Metabolic Reprogramming in Exercise-Attenuated Osteoporosis: a Narrative Review

BACKGROUND: The aging population has led to a significant increase in the prevalence of osteoporosis, making it an important public health issue. Emerging evidence suggests that osteoporosis is related to glucose metabolic reprogramming (GMR). Exercise is an effective non-pharmac...

The gut-inflammation-hearing axis in diabetic patients aged 30–55: exploring microbiome-mediated pathways to auditory complications

Abstract Background/Objectives Hearing impairment is an underrecognized yet prevalent complication of type 2 diabetes mellitus (T2DM), but the underlying mechanisms remain poorly understood. This study investigated whether gut microbiota dysbiosis contributes to diabetic hearing...

Exercise-Induced Regulation of Bone Remodeling via Mitophagy: A Review of Current Evidence

Bone remodeling imbalance represents the fundamental pathological basis of osteoporosis. Exercise is broadly regarded as a valuable non-pharmacological strategy for preventing and managing osteoporosis; however, the precise molecular mechanisms through which exercise modulates bo...