Shandong Eye Hospital

The Matricellular Protein CCN1 Induces Corneal Stromal Cells Senescence and Inflammation to Trigger Extracellular Matrix Remodeling in Keratoconus

Purpose: Keratoconus (KC) is a multifactorial corneal degenerative disorder characterized by reduced extracellular matrix (ECM) and cellular content. This study investigates the role and mechanism of cellular communication network factor 1 (CCN1) in KC progression. Methods: The e...

Role of Autophagy in Scleral Remodeling During Form‐Deprivation Myopia

Autophagy has been implicated in tissue remodeling, but its role in scleral remodeling during myopia development and in atropine-mediated myopia control remains unclear. We investigated this issue using complementary in vitro and in vivo models. Human scleral fibroblasts (HSFs) w...

Different vault outcomes following implantable collamer lens implantation in eyes with ciliary body cysts: a case report

Ciliary body cysts are common incidental findings during preoperative screening for implantable collamer lens (ICL) implantation. Although their presence is generally not considered a contraindication to surgery, cysts extending into the ciliary sulcus may influence haptic seatin...