Services Australia

Jaundice and Mycoplasma ovis in Australian sheep

Mycoplasma ovis has been known to infect Australian sheep for >60 years. The infection can induce haemolytic anaemia with associated ill-thrift and occasionally mortality. The haemolysis can also lead to jaundice in subclinically infected sheep sent for slaughter. Jaundiced lamb...

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

ABSTRACT Synaptic dysfunction is a major driver of cognitive decline in Alzheimer's disease (AD), yet its extent and molecular basis in the retina remain poorly defined. We integrated postmortem retinal and matched brain histopathology with ultrastructural, proteomic, biochemical...

Predictive validity of the Addenbrooke’s cognitive Examination III for on-road driving outcomes in a clinical fitness-to-drive population: a prospective cohort study

Background Evidence-based fitness-to-drive assessment must balance public safety and fairness. Cognitive screens are commonly used, but must be accurate in high-stakes contexts. The predictive utility of the Addenbrooke’s Cognitive Examination III (ACE-III) for driving outcomes r...