Seoul Medical Center

Association of Estimated Arterial Stiffness with Collateral Status and Functional Outcome after Endovascular Thrombectomy: A Secondary Analysis of the OPTIMAL-BP Trial

PURPOSE: Estimated pulse wave velocity (ePWV) is a surrogate of arterial stiffness that may influence stroke outcomes and potentially affect collateral circulation. We examined the association of ePWV with collateral status and 3-month functional outcome after successful endovasc...

Age-Stratified Median Effective Dose of a Continuous Remimazolam Maintenance Infusion for Moderate Sedation During Spinal Anesthesia: A Prospective Up-and-Down Dose-Finding Study

Background and Objectives: Remimazolam is an ultra-short-acting benzodiazepine suitable for continuous infusion; however, evidence regarding its maintenance infusion rate for moderate sedation during spinal anesthesia across age strata is limited. We aimed to estimate and compare...

Nationwide Multicenter Laboratory-Based Analysis of Varicella-Zoster Virus IgG and IgM Seropositivity in Korea, 2014–2024

Background: Varicella-zoster virus (VZV) remains an endemic, vaccine-preventable infection in Korea, despite high national vaccination coverage. Understanding long-term population immunity trends is essential for refining the disease-control and immunization policies. In this nat...

Vascular Imaging Features and Time-Specific Recurrence Risk After Craniocervical Artery Dissection

Background and ObjectivesCraniocervical artery dissection (CCAD) is a major cause of stroke in young adults, yet its recurrence risk remains poorly defined because of delayed enrollment in prior research. We aimed to determine the temporal distribution of recurrent ischemic strok...

Modeling thermal cross-talk and cooling kinetics in clustered melanosomes after nanosecond laser heating

Abstract Selective photothermal confinement is commonly evaluated using the thermal relaxation time (TRT) of individual absorbers, but ultrastructural studies have shown that epidermal melanosomes are organized in clustered arrangements that may alter post-pulse cooling. Here, we...

Gait parameters and plantar pressure estimation from the prosthesis evaluation questionnaire using a synthetic-data-enhanced supervised learning model: A proof-of-concept study

Understanding the impact of lower limb prostheses on gait is crucial for improving users’ quality of life. To this end, quantitative gait analysis provides objective and detailed information but is time-consuming and resource-intensive, whereas qualitative usability and ergonomic...

Predictors of Early Versus Late Atrial Tachyarrhythmia Recurrence After Cryoballoon Ablation by Atrial Fibrillation Type

ABSTRACT Introduction Patient characteristics and predictors of early (ERAT) and late (LRAT) recurrence of atrial tachyarrhythmia by atrial fibrillation (AF) type after cryoballoon ablation (CBA) remain poorly defined. Methods Using the Korean Heart Rhythm Cryoballoon Registry (1...

Repeated Short-Term Intratracheal Exposure to Urban Particulate Matter Has No Apparent Adverse Effects on Female Reproductive Outcomes in Mice

Urban particulate matter (UPM) is a major environmental pollutant known to induce systemic inflammation. While its respiratory toxicity is well-documented, the potential vulnerability of the female reproductive system to inhaled UPM remains a critical concern. In this study, we e...

Identification of a Pathogenic RECQL4 1.6-kb Deletion–Insertion in a Neonate with Atypical Skeletal Phenotype of Baller–Gerold Syndrome Using Rapid Whole-Genome Sequencing

Mi-Ae Jang, M.D., Ph.D., Ja-Hyun Jang, M.D., Ph.D., Jin Kyu Kim, M.D., Ph.D., Joonhong Park, M.D., Ph.D., Go Hun Seo, M.D., Ph.D., Misun Yang, M.D., Ph.D., Yun Sil Chang, M.D., Ph.D., and Hyun Ho Kim, M.D., Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2026.0102