Secretaría de Salud de Jalisco

Two Transcriptomic Analyses Converge on a Five-Gene Core for Colorectal Cancer Discrimination: External Validation in Independent Tissue Cohorts

Background/Objectives: Colorectal cancer (CRC) is a leading cause of neoplasia-related morbidity and mortality worldwide and the first cause of cancer death in Mexico, where early detection remains a challenge, and reliable molecular biomarkers could support earlier diagnosis. Tr...

Molecular Detection and Phylogenetic Characterization of CPV-2c in Apparently Healthy Domestic Cats in the Guadalajara Metropolitan Area, Mexico

Carnivore protoparvovirus 1 variants (CPV-2a, CPV-2b, CPV-2c) have progressively expanded their host range to domestic cats (Felis catus), causing subclinical infection or panleukopenia-like disease. CPV-2c dominates among dogs in Western Mexico, but its presence in the local fel...

Sustained iron-nanoparticle exposure reveals concentration-dependent enhancement and inhibition during continuous hydrogen production from brewer's spent grain hydrolysate

Iron-based nanoparticles can enhance dark fermentation, but sustained-exposure effects remain unclear. This study aimed to investigate continuous supplementation with iron (III) oxide nanoparticles (FeNPs) during dark-fermentative hydrogen production from brewer's spent grain (BS...

Poloxamer/HPMC/Carbopol-Based Thermosensitive Hydrogel Loaded with Ibuprofen for Potential Vaginal Drug Release

Vaginal drug delivery offers a critical route for local treatments but is limited by short formulation residence times. This study describes a thermosensitive in situ gel prepared by the cold-dissolution method from a ternary blend of Pluronic F127, Carbopol 940, and HPMC for loc...

Thinner femoral cortical thickness in children with knee hemophilic arthropathy

A cross-sectional study was performed to compare the cortical femoral shaft between the leg with knee hemophilic arthropathy and the contralateral leg. Children with hemophilic arthropathy were included. Joint evaluation was made using the Hemophilia Joint Health Score 2.1 (HJHS...