Second Hospital of Nanchang

Non-prescription supportive care interventions for anticancer therapy-induced oral mucositis: protocol for a systematic review and meta-analysis

Abstract Background Oral mucositis (OM) is a common and debilitating complication of anticancer therapies, frequently resulting in pain, nutritional impairment, and potential treatment interruption. While several pharmacologic and device-based interventions have been evaluated, l...

Initial response and long-term prognostic risk factors in pediatric ITP

To explore the clinical features and prognostic factors for initial response and long-term prognosis of pediatric immune thrombocytopenia (ITP). A retrospective cohort study of 910 cases of pediatric patients with ITP was conducted. Demographic data, platelet counts, triggers, bl...

Secondary prevention of cancer therapy-induced thrombocytopenia with hetrombopag in breast cancer: a multicenter, randomized, exploratory phase II trial

Abstract Background: Cancer therapy-induced thrombocytopenia (CTIT) is a common complication of anti-tumor therapy, leading to treatment delays or interruptions, increased bleeding risk and compromised outcomes. In the present study, we aimed to evaluate the efficacy and safety o...

Surgical approaches for screw fixation of calcaneal fractures: a systematic review

To systematically review and summarize the evidence related to different screw configurations in the internal fixation treatment of calcaneal fractures. This systematic review (PROSPERO registration CRD420261389986) employed a comprehensive literature search of PubMed/MEDLINE, Em...