Second Affiliated Hospital of Xuzhou Medical College

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

ABSTRACT Tumor‐derived extracellular vesicles (EVs) are emerging as critical mediators of metabolic adaptation, yet their role in orchestrating ferroptosis resistance within the tumor microenvironment remains poorly understood. Here, we show that highly malignant osteosarcoma (OS...

New-onset headache and early aggravation of pre-existing headache after anterior cervical discectomy and fusion: a retrospective cohort study

Pre-existing cervicogenic headache often improves after anterior cervical discectomy and fusion (ACDF); however, new-onset postoperative headache and early aggravation of pre-existing headache remain poorly characterized. This study evaluated these outcomes separately and assesse...

Unicompartmental versus total knee arthroplasty in patients aged 60 years or older with isolated medial knee osteoarthritis and correctable varus deformity > 15° to 20°: a five-year retrospective cohort study

The role of unicompartmental knee arthroplasty (UKA) in patients aged ≥ 60 years with isolated medial knee osteoarthritis and correctable varus > 15° remains controversial. Five-year UKA and total knee arthroplasty (TKA) outcomes were compared in patients with varus > 15° to 20°....