Second Affiliated Hospital of Inner Mongolia Medical University

Lachnospiraceae in the Food–Gut Axis: A Critical Review of Dietary Modulation, Immune Regulation, and Translational Barriers

The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short-chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distingu...

Risk factors for postoperative sleep disturbance after total joint arthroplasty: a systematic review and meta-analysis

Abstract Objective Postoperative sleep disturbance (PSD) is a common complication following total joint arthroplasty (TJA) and impairs functional recovery. Numerous studies have identified potential risk factors for PSD; however, existing evidence is derived primarily from small...

Exosomal miR-22-3p targets p53 to regulate endometrial epithelial cell function in the pathogenesis of endometriosis

Endometriosis (EMs) is a widespread gynecological disease, affecting approximately 6-10% of females of child-bearing age. Despite its significant influence on women's health, the specific pathophysiology remains unclear. The enrichment of miR-22-3p in exosomes has been implicated...

Patellar fixation in MPFL reconstruction: a network meta-analysis comparing bone tunnel and suture anchor techniques

Although medial patellofemoral ligament (MPFL) reconstruction has become the cornerstone procedure for recurrent patellar instability (RPI), the optimal patellar-side fixation technique remains debated. Direct head-to-head comparisons are scarce, and traditional pairwise meta-ana...

A Robust Mitochondria‐Targeted Photosensitizer Synergizes With Cisplatin Chemotherapy for Enhanced Antitumor Immunity

ABSTRACT Chemotherapy remains a major strategy for cancer treatment, with cisplatin widely used as a first‐line agent for diverse malignancies. Although cisplatin efficiently induces tumor cell death through DNA damage, its therapeutic efficacy is often limited by the development...

Association of ovarian inflammation and hormonal dysregulation: a candidate mechanism underlying polycystic ovary syndrome

Abstract Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by female infertility, menstrual irregularities, and hormonal imbalance, leading to impaired reproductive health. Hyperandrogenemia is considered a central endocrine feature and a ke...