Science Foundation Ireland

Shared household environment structures the gut microbiota in a large family cohort with central areolar choroidal dystrophy

Central areolar choroidal dystrophy (CACD) is a rare monogenic hereditary retinal dystrophy characterised by progressive retinal pigment epithelium and choriocapillaris atrophy, photoreceptor loss, oxidative stress, and chronic inflammation. Emerging evidence suggests that the gu...

Predictive normative modeling of neurocognitive performance in Irish jockeys using regression and neural quantile methods

This study presents a comprehensive evaluation of regression-based methods for generating normative data for neuropsychological test scores, using retrospective cross-sectional data from Irish jockeys between 2010 and 2024. The analysis focuses on four key cognitive assessments u...