Schwarzwald-Baar Klinikum

Measuring the Posterior Airway Space: Inaccuracies in Taking and Interpreting Lateral Cephalograms

Abstract Objectives Although lateral cephalograms (LCs) are often used to measure the posterior airway space (PAS), little consensus has been reached on standardised PAS measurement procedures, which hinders reproducibility. This study uses LCs to evaluate the reliability of PAS...

A biomechanical comparison of closed-reduction osteosynthesis techniques for fractures of the ulnar styloid

BACKGROUND: Ulnar styloid fractures (USF) are frequently underestimated and can contribute to clinically relevant wrist instability and impaired functional outcomes. Several osteosynthesis techniques are available for the treatment of unstable USF. This study aims to compare the...

DECIDER-2: Prospective randomized multicenter phase III trial of decitabine and venetoclax administered in combination with all-trans retinoic acid or placebo in patients with acute myeloid leukemia who are ineligible for induction chemotherapy

Abstract Background Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of the combination of venetoclax (VEN) with azacitidine (AZA) or decitabine (DAC) in the European Union in 2021 for the treatment of patients wit...