Sapporo Medical University

Stent-graft placement for an axillosubclavian artery injury in a pediatric patient: A case report

Axillosubclavian artery injury is a rare traumatic vascular injury associated with a high mortality rate. Therefore, rapid diagnosis and appropriate treatment selection are critical for patient survival. Although endovascular stent-graft placement has emerged as a less invasive a...

Developing a Comprehensive Public Health Nursing Practice Model for Promoting Social Inclusion Among Populations Experiencing Social Exclusion: A Qualitative Study

ABSTRACT Aims To develop a comprehensive practice model delineating public health nursing practices that promote social inclusion and illustrate their outcomes in Japan. Design Qualitative descriptive research design. Methods Semi‐structured interviews were conducted with 12 publ...

Changes in Bladder Outlet Obstruction After Photoselective Vaporization of the Prostate in Men With and Without Detrusor Underactivity: A Retrospective Propensity Score‐Matched Study

ABSTRACT Objectives To compare symptomatic improvement after photoselective vaporization of the prostate (PVP) between patients with and without detrusor underactivity (DU), together with objective changes in urodynamic parameters assessed by pressure‐flow study (PFS). Methods Th...

In vitro models to study novel pathogenesis in therapy for human endometriosis

Endometriosis is an estrogen-dependent chronic disease characterized by the growth and migration of endometriotic tissue. Various growth factors, cytokines and tight junction proteins, contribute to the progression of endometriosis; however, the mechanisms underlying the chronic...

Effects of early parent–child relationships on adult psychological traits, genetic temperament, and health status: An analysis using the structured association technique （SAT）

Psychological traits and genetic temperaments that contribute to long-term illness, such as depression, cancer, and lifestyle disease, may be shaped by early parent-child relationships, but their combined effects remain unclear. This study used the structured association techniqu...

Physician-modified fenestrated/inner-branched endovascular aortic repair for distal aortic arch aneurysm after stent graft migration: a case report

Abstract Backgrounds Open surgical repair remains the gold standard for aortic arch aneurysms, and endovascular treatment options are limited in high-risk patients. We report successful treatment of a distal aortic arch aneurysm using physician-modified fenestrated/inner-branched...

Tandospirone for antidepressant-intolerant persistent postural-perceptual dizziness: A case series based on an otolaryngology–psychiatry collaborative care model

Introduction: Persistent postural-perceptual dizziness is typically managed with serotonergic antidepressants; however, treatment continuation is frequently hindered by adverse effects. Pharmacological alternatives for patients with antidepressant intolerance remain poorly define...

Association Between Preoperative Gluteal Muscle Quality on CT and Buttock Claudication After EVAR With Internal Iliac Artery Embolization

Objective: Internal iliac artery (IIA) embolization is frequently performed during endovascular aneurysm repair (EVAR) to secure an adequate distal sealing zone or to treat iliac artery aneurysms; however, it may result in postoperative buttock claudication. This study investigat...

Altered balance between circulating T follicular helper and T peripheral helper cells and regulatory B cells in COPD: an exploratory cross-sectional study

Abstract Background Tertiary lymphoid organs (TLOs) develop in the lungs of patients with chronic obstructive pulmonary disease (COPD) and may contribute to persistent inflammation. CXCL13 is involved in lymphoid follicle organization, but the relationships among circulating T fo...

Preoperative Medial Meniscus Extrusion Predicts Varus Correction Loss After 5 Years Despite Stable Bony Alignment After Medial Opening‐Wedge High Tibial Osteotomy

PURPOSE: To determine if medial meniscus extrusion (MME) impacts postoperative alignment and varus correction loss after medial opening-wedge high tibial osteotomy. METHODS: We retrospectively reviewed patients who underwent medial opening-wedge high tibial osteotomy for medial c...

Serum soluble Fas levels and incidence of biliary tract cancer in a nested case-control study

Abstract Background: Soluble Fas (sFas) plays multiple roles in tumorigenesis and cancer dissemination by avoiding apoptosis via connection to Fas ligand. We assessed associations of serum sFas levels with the incidence of extrahepatic biliary tract cancer (eBTC) in a prospective...

Evaluation of clinical prognostic factors for radium-223 therapy in castration-resistant prostate cancer with bone metastases: the KYUCOG-1901 study

We evaluated clinical factors associated with symptomatic skeletal events (SSEs), radiographic progression-free survival (rPFS), and overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases treated with radium-223 (Ra-223)...

Intravenous Infusion of Mesenchymal Stem Cells Enhances Long-Tract Reorganization That Circumvents the Lesion in a Rat Staggered Hemisection Spinal Cord Injury Model

Background/Objectives: Non-contiguous dual spinal cord injuries are associated with poor neurological outcomes, probably due to reduced spared-tract bridges for compensatory reorganization. Intravenous (IV) infusion of mesenchymal stem cells (MSCs) promotes recovery after SCI. Ho...

Efficacy and safety of upadacitinib for Crohn’s disease in patients in East Asia: a post hoc analysis of randomized phase 3 studies

Abstract Background Upadacitinib is an oral Janus kinase inhibitor approved for the treatment of moderate-to-severe Crohn’s disease (CD). This post hoc analysis reports the efficacy and safety of upadacitinib for CD in patients in East Asia enrolled in the phase 3 clinical trials...

Pretreatment Geriatric Nutritional Risk Index in RADPLAT-treated Patients With Oral Squamous Cell Carcinoma: A Pilot Study

Background/Aim: Pretreatment nutritional and inflammatory indices have been associated with prognosis in patients with oral squamous cell carcinoma (OSCC) undergoing surgery or chemoradiotherapy; however, their prognostic significance in patients treated with superselective intra...

Emergency care competencies for non–emergency medicine specialists in Japan: a modified Delphi study

Abstract Background Physicians from specialties other than emergency medicine (non-EM specialists) provide first-contact emergency care in many health systems. Existing emergency care courses and competency frameworks address resource-limited first-contact care or rural self-suff...

Comparative in vivo evaluation of colistin resistance determinants in Escherichia coli clone ST131

Background Colistin is a last-resort antimicrobial for multidrug-resistant (MDR) Gram-negative infections. Health risks associated with colistin resistance are commonly inferred from resistance phenotypes, despite limited in vivo evidence linking resistance determinants to pathog...