Santa Maria Nuova Hospital

Migraine in Real-World Clinical Practice: Patient Burden, Healthcare Utilization and Unmet Needs—A Cross-Sectional Analysis of the I-GRAINE Study

What are the main findings?Migraine care in Italy is characterized by a mismatch between healthcare resource utilization and clinical needs, with limited primary-care involvement, repeated specialist consultations, and healthcare nomadism.Healthcare resource utilization is substa...

A rare case of abdominal actinomycosis mimicking ovarian cancer with presumed hepatic involvement and abdominal wall involvement

species. Because of its infiltrative growth, abscess formation, and fibrotic reaction, it may closely mimic malignant disease. We report the case of a 53-year-old woman presenting with abdominal pain and a palpable epigastric mass. Imaging showed a pelvic mass with abdominal wall...

Stereotactic Prostate Cancer Ablative Re‐Irradiation: A Systematic Review and Meta‐Analysis (SPARE)

ABSTRACT Background Stereotactic ablative radiotherapy (SABR) is emerging as an alternative treatment for patients with locally recurrent prostate cancer after previous radiation. This approach allows for precise target coverage while limiting toxicity to surrounding organs. Howe...

Targeting KPC-Producing Klebsiella pneumoniae Biofilms: Genomic Profiles, Clinical Outcomes and Novel Combinations

New beta-lactam/beta-lactamase inhibitor combinations (BL/BLICs) are licensed for Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) infections. However, data regarding their efficacy against bacterial biofilms and the potential of synergistic comb...

Bladder multilithiasis across different clinical scenarios: Multimodality imaging findings, differential diagnosis, and complication assessment in 4 patients

Bladder calculi are an uncommon form of urolithiasis in developed countries and are usually associated with urinary stasis, bladder outlet obstruction, chronic catheterization, recurrent urinary tract infections, and neurogenic bladder dysfunction. Although their diagnosis is oft...

Buddy Wire–Augmented Intravascular Lithotripsy in Refractory Calcified Coronary Lesions: A Five‐Case Series

Heavily calcified coronary lesions remain a major challenge in percutaneous coronary intervention (PCI), often limiting the effectiveness of intravascular lithotripsy (IVL). We report a five-case series in which IVL failed to achieve adequate lesion modification but was successfu...

Thalamocortical connectivity and nucleus-specific thalamic dysfunction in temporal lobe epilepsy: an integrative review

Temporal lobe epilepsy (TLE) is increasingly recognized as a distributed network disorder extending beyond mesial temporal structures. Among the brain regions implicated in epileptic network organization, the thalamus has emerged as a key hub due to its extensive structural and f...