Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi

Immunohistochemical investigation of suprabasin, isthmin-1, and podocalyxin immunoreactivity in basal cell carcinoma and trichoblastoma/trichoepithelioma

Objective Basal cell carcinoma (BCC) and trichoblastoma/trichoepithelioma (TB/TE) are skin tumors that may exhibit similar histopathological features. This study aimed to examine the immunoreactivity of suprabasin (SBSN), isthmin-1 (ISM-1), and podocalyxin (PODXL) BCC and TB/TE,...

Early functional and operative outcomes of three open surgical approaches compared with closed reduction and percutaneous pinning in Gartland type III pediatric supracondylar humerus fractures

Supracondylar humerus fractures (SHFs) are commonly treated with closed reduction and percutaneous pinning (CRPP); however, open reduction is required in selected cases. To compare early functional and operative outcomes of anterior, lateral, and posterior open reduction techniqu...

Redefining leptomeningeal metastasis in non–small cell lung cancer: From terminal complication to molecularly managed disease

Leptomeningeal disease (LMD) is one of the most devastating complications of advanced non-small cell lung cancer (NSCLC), historically associated with profound neurologic morbidity and poor survival. Advances in cerebrospinal fluid (CSF)-based diagnostics, improved molecular char...

Neuropeptide Y levels, social functionality, and cognitive insight in patients with schizophrenia in symptomatic remission: A case-control study

Objective This case-control study aimed to investigate serum neuropeptide Y (NPY) levels in patients with schizophrenia in symptomatic remission and to examine their relationship with social functioning and cognitive insight. Methods Forty patients with schizophrenia in symptomat...

Factors associated with treatment delay and PPE use in occupational corneal foreign body injuries: a cross-sectional study

Objective This study aimed to evaluate characteristics, first aid and PPE use among patients with occupational corneal foreign body (CFB) injuries.Methods A cross-sectional study included 92 male patients treated at Harran University. Data on demographics, job type, injury cause,...

Simultaneous Reconstruction of Early Orbital Implant Exposure and Lower Eyelid Symblepharon Using an Oral Mucosal Membrane Graft Following Evisceration

A 72-year-old male patient presented with early orbital implant exposure and lower eyelid symblepharon after evisceration surgery performed at an outside center after severe ocular penetrating trauma. A single-stage reconstruction was performed. After release of the lower eyelid...

Clinicopathological Features, Tumor Localization and Treatment Outcomes in Paraganglioma: A Single-Center Medical Oncology Cohort

Background/Objectives: Paragangliomas (PGLs) are rare neuroendocrine tumors, and data describing them from a medical oncology perspective are limited. We characterized clinicopathological features, tumor localization, and treatment outcomes. Methods: We retrospectively analyzed 4...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...