Sanford Consortium for Regenerative Medicine

Autophagy Flux Is Remodeled Sex‐ and Cell Type‐Specifically During Human Aging, and Is Linked to Reduced Physical Function in Older Adults

ABSTRACT Autophagy is widely proposed to decline with age; however, direct evidence across human cell types remains limited. Moreover, it is unclear whether age‐associated changes in autophagy‐gene transcription are accompanied by corresponding changes in autophagic activity, and...