San Francisco Department of Public Health

Developing a drug-level feedback adherence counseling intervention for young MSM in the U.S.

Background: Young men who have sex with men (MSM) in the U.S. have suboptimal adherence to oral tenofovir-based pre-exposure prophylaxis (PrEP), undermining HIV prevention goals. Drug-level feedback using urine point-of-care tenofovir assays has improved adherence in Eastern and...

Differentiated service delivery and peer-led digital messages to strengthen health outcomes among young men and non-binary persons who have sex with men in Brazil

Despite the disproportionate burden of HIV among young men and non-binary persons who have sex with men (YMSM/NB) in Latin America, interventions among this population are scarce. We aimed to evaluate changes in health outcomes associated with a targeted intervention. Conectad@s...

Delivering Long-Acting Injectable Cabotegravir PrEP to People Experiencing Homelessness and People Who Use Drugs

Long-acting injectable cabotegravir (CAB-LA) may be particularly advantageous for preventing HIV among people experiencing homelessness (PEH) and people who use drugs (PWUD), populations at high HIV risk with poor oral pre-exposure prophylaxis (PrEP) outcomes. In a retrospective...

“I Know Far More Dead People Than I Do Live Ones”: Social Isolation Among Older Adults Who Use Stimulants

BACKGROUND: Social isolation is associated with poor physical health and premature mortality. Midlife and older adults who use stimulants (cocaine or methamphetamine) may be especially vulnerable to social isolation. METHODS: We conducted in-depth semi-structured interviews with...

Oral Nicotine Pouch Use and Associations with Periodontal Status and Salivary Microbiome Dysbiosis

OBJECTIVES: Oral nicotine pouches (ONPs) are increasing in use, yet data on potential oral health effects are scarce. We evaluated whether ONP use is associated with clinical periodontal measures and salivary microbiome dysbiosis in a field-based regional sample. We recruited fir...

Assessing acuity in pediatric emergency department triage: performance of a large language model

Pediatric triage performance varies across emergency departments (ED), contributing to ongoing challenges in pediatric emergency care. There is growing interest in using large language models (LLMs) to support more consistent triage decision-making in children. We evaluated an LL...