Samueli Institute

TRAM-AI: A Framework for Transparency in Reporting of Medical Imaging Datasets for Artificial Intelligence Development

Purpose To develop and evaluate TRAM-AI, a consensus-based checklist for verifying whether medical imaging datasets described as publicly accessible are functionally usable for AI development. Materials and Methods A modified Delphi study was conducted. A steering committee gener...

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

The tumor microenvironment (TME) is a complex and heterogeneous milieu encompassing biological and biochemical events and diverse physical, chemical, and mechanical interactions between tumor and stromal cells. This heterogeneity plays a pivotal role in regulating tumor progressi...

Groundwater Dynamics and Aquifer–Stream Interactions in California’s San Joaquin River Basin: Insights from a Coupled SWAT+ Gwflow Framework

Quantifying groundwater depletion and aquifer–stream interactions in intensively irrigated basins remains a critical challenge for sustainable water management. This study numerically examines these issues in the San Joaquin River Basin (SJRB) using the coupled SWAT+ gwflow frame...

Subanesthetic nitrous oxide alters large-scale network organization and insula connectivity during visual stimulation

Pharmacological agents that alter consciousness, including classic psychedelics and non-classic agents such as nitrous oxide, are known to affect multiple domains of conscious experience, including visual perception. While most neuroimaging studies rely on resting-state data to c...