Samarkand State Medical Institute

The Transformation of the Microenvironment: From Observer to Coordinator in Monoclonal Gammopathy of Undetermined Significance (MGUS) to Myeloma Development

ABSTRACT Monoclonal gammopathy of undetermined significance (MGUS) is a common asymptomatic plasma cell disorder and the major precursor state of multiple myeloma (MM). Although progression is partly shaped by intrinsic genetic and epigenetic changes within the plasma cell clone,...

MORPHOLOGICAL AND MICROBIOLOGICAL CHANGES IN THE INTESTINAL TRACT FOLLOWING EXPERIMENTAL CHOLECYSTECTOMY

Gallstone disease (GLD) is a disease of the hepatobiliary system, characterized by the formation of changes in the internal bile ducts of the liver, the common bile duct, and the gallbladder. Gallstone disease, according to most statistical analyses, is more common in young and m...