Sakarya Eğitim ve Araştırma Hastanesi

Clinical and pathological characteristics of mucinous adenocarcinoma in colon cancer: comparison with classic adenocarcinoma

Mucinous adenocarcinoma of the colon is defined by extracellular mucin occupying at least 50% of the tumour. Although it is often regarded as a distinct histological subtype, its clinicopathological profile remains variable across published series. We compared mucinous and classi...

Blood Pressure and Angina-Related Health Status During Benidipine Therapy: A Multicenter Real-World Cohort Study

Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...

Beyond Traditional Continuous Performance Tests: The Incremental Diagnostic Value of Distractor-Embedded Paradigms

Objective Distractor-embedded continuous performance test (CPT) paradigms have been developed to enhance the ecological validity and diagnostic precision of attention-deficit/hyperactivity disorder (ADHD) assessment. This study aimed to quantitatively synthesize the diagnostic pe...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...