Saiseikaisenri Hospital

Rapidly progressive interstitial lung disease with an organizing pneumonia-dominant high-resolution computed tomography pattern in systemic lupus erythematosus: a case report and literature review

Among pulmonary involvements of systemic lupus erythematosus (SLE), interstitial lung disease (ILD) is an infrequent but clinically significant complication, with fatal cases reported as "acute lupus pneumonitis" and associated with increased mortality. However, SLE-ILD remains i...

Neutrophil Extracellular Traps Formation Adhering to Cholesterol Crystals Modulates Inflammatory Cytokines Release and Promotes Their Disruption: Insights In Situ Touch-imprints Method From Non-obstructive General Angioscopy

Both macrophages and neutrophils are recognized as innate immune cells; the former engulf cholesterol crystals (CCs) while secreting NLRP3, which also promote inflammatory responses and drive the latter into atherosclerotic plaques. Moreover, recent studies have implied a critica...