Saint Louis University Hospital

Neuronal intermediate filament neurologic autoimmunity in a patient with Merkel cell carcinoma receiving pembrolizumab

Abstract Background Neuronal intermediate filament (NIF) autoimmunity is an uncommon paraneoplastic neurologic syndrome that has increasingly been recognized in association with immune checkpoint inhibitor (ICI) therapy. Merkel cell carcinoma is among the malignancies most freque...

Sepsis in the major burn patient

Abstract Background Sepsis in the context of major burn injury presents a significant challenge to clinicians. It affects a substantial proportion of patients with major burn injury and is the leading cause of death in those that survive to hospital. Due to the complex and profou...

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the trea...

Palliative and end-of-life care on the battlefield: a scoping review

Abstract Background Modern conflicts have brought about a paradigm shift in military medicine. In Prolonged Field Care, recommendations have so far focused on damage control and care aimed at ensuring survival. But, particularly in large scale combat operation, not all patients w...

Performance of the iBox Prognostication System in African American Kidney Transplant Recipients

Background: The iBox is a validated prognostication system that predicts long-term death-censored graft loss in kidney transplant recipients, but its performance in the specific population of African American recipients has not been fully studied. Methods: We conducted a multicen...

Hip and groin pain in physically active adults with a focus on terminology, clinical examination and imaging: A formal ESSKA‐EHPA‐ESMA Consensus

Abstract Purpose This European Society of Sports Traumatology, Knee Surgery and Arthroscopy–European Hip Preservation Associates–European Sports Medicine Association (ESSKA‐EHPA‐ESMA) formal consensus aims to provide evidence‐ and expert opinion‐based recommendations for the term...

Multichamber Myocardial Strain for Cardiovascular Risk Stratification in Liver Transplant Recipients Using Interpretable Machine Learning

BACKGROUND: Cardiovascular events are a leading cause of mortality after liver transplantation (LT), and existing risk scores incompletely capture myocardial vulnerability. OBJECTIVES: The objective of the study was to evaluate whether pre-LT myocardial strain improves machine-le...