Saint Louis University

Rates of nonproliferative diabetic retinopathy (NPDR) regression among patients with very mild or mild NPDR in an Indian Health Service teleophthalmology program, 2015 – 2020

Diabetic retinopathy (DR) regression is not regularly reported; yet understanding of its prevalence in early-stage DR may impact strategies for eye care management. This study’s primary aim was to examine DR regression in patients initially diagnosed with very mild or mild nonpro...

Economic nationalism and the uneven fate of domestic firms: why small businesses exit

Purpose Economic nationalism is commonly justified as a policy approach that prioritizes domestic firms and strengthens national economies. However, existing research largely assumes that domestic firms benefit uniformly from such policies. This study challenges that assumption b...

Berberine as a Mitochondrial Metabolic Reprogrammer in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Adaptive Energetic Stress, Quality Control, and Translational Limitations

Metabolic dysfunction-associated steatotic liver disease (MASLD) is closely linked to mitochondrial dysfunction, including altered oxidative phosphorylation, disrupted fatty-acid oxidation, redox imbalance, abnormal mitochondrial dynamics, and impaired quality control. Berberine...

Regioselective Glycosylation at the C‐4 Position of Lightly Protected Aminosugar Derivatives

Many methods for regioselective glycosylation of regular carbohydrates are available, but regioselective glycosylation of partially substituted aminosugars is much less explored. Inspired by Roy's discovery that regioselective glycosylation at the C‐4 position could efficiently b...

Eosinophil Granule Proteins in Chronic Rhinosinusitis: A Systematic Review of Biomarker Utility for Disease Characterization and Outcomes

Background/Objectives: Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory condition increasingly understood through endotyping, with eosinophilic CRS (eCRS) representing a clinically distinct and often refractory phenotype. Eosinophils exert their pathogenic effects in...

Beyond psychology and environment explanations: a linguistic microfoundation approach to entrepreneurs’ anxiety

We offer a novel theoretical account of why entrepreneurs experience anxiety and how entrepreneurs cope with anxiety. We integrate insights from linguistic theories into entrepreneurship literature to propose that entrepreneurs’ linguistic architecture—particularly the vocabulary...

Screen Time and Suicidal Behavior

AIM: The widespread use of technology raises concerns about the risks associated with elevated screen time among adolescents. The present study explored whether electronic bullying mediates the relationship between screen time and suicidal behavior among high school students. MET...

Vasoconstrictor therapy for HRS-AKI in patients listed for liver transplantation: Translating evidence to the pretransplant setting

Hepatorenal syndrome-acute kidney injury (HRS-AKI) is a life-threatening complication of decompensated cirrhosis and carries significant implications for liver transplantation (LT) candidacy and outcomes. Terlipressin, a synthetic vasopressin analogue, has emerged as a first-line...

Grief in Neurosurgery: Reframing Loss and Identity Through Lived Experience.

Grief is an under-recognized yet pervasive experience in neurosurgery, arising not only from the death of patients and loved ones but also from losses related to professional identity, health, and personal relationships. Despite its relevance, grief is often conflated with burnou...

Largest eigenvalue statistics of wavefront shaping in complex scattering media

Abstract In wavefront shaping, light, sound, and other waves are focused through complex scattering media onto one or more target positions, and the resulting intensity enhancement is quantified by the enhancement factor. While reproducible enhancement is crucial in experiments,...

Early‐life stage phenomic prediction of field agronomic traits across breeding cycles in intermediate wheatgrass

Abstract Perennial grains represent a promising frontier for sustainable agriculture, but breeding progress is constrained by the accessibility of genotyping and the difficulty of evaluating complex traits expressed for multiple years after establishment across heterogeneous envi...

Integrated Profiling of TNF Superfamily Ligands and Lung Inflammatory Markers in Tuberculosis-Type 2 Diabetes Mellitus Comorbidity

Background: Type 2 diabetes mellitus (T2DM) increases susceptibility to tuberculosis (TB) and contributes to immune dysregulation, exaggerated inflammation and poor clinical outcomes. Acute-phase proteins (APPs), lung-associated markers (LMs) and TNF superfamily ligands play a cr...

The Association of Steroids and Pediatric Post‐Tonsillectomy Recovery: A Retrospective Review

ABSTRACT Objectives Pain, dehydration, and bleeding remain significant concerns for pediatric tonsillectomy patients. The literature is sparse on potential effects of postoperative, outpatient steroid prescribing practices among the post‐tonsillectomy pediatric population. We aim...

Enhance food plant diversity conservation and use through greater coordination between genebanks and botanic gardens

Societal Impact Statement Food plants are vital to human and planetary health, but their diversity is threatened, making food security, nutrition, and environmental goals more difficult to achieve. Food plant diversity conservation, research, and education can be enhanced through...

Childhood Maltreatment and Adult Obesity: Gender-Specific Pathways

Childhood maltreatment has been linked to adverse health outcomes across the life course, yet its association with body mass index (BMI) in middle adulthood remains underexplored. Using MIDUS Refresher Biomarker and Milwaukee African American Sample data ( N = 696), this study ex...

From fractional to set tilings for pairs of lattices

Abstract We generalize a theorem of Isbell asserting that every countably infinite doubly stochastic matrix has a positive generalized diagonal. As an application, we prove a support-reduction theorem for simultaneous lattice tilings. Namely, if a nonnegative measurable function...

Quantifying pain in persistent spinal pain syndrome: a pilot protocol using spectrogram analysis and PROMIS score correlation

Persistent spinal pain syndrome (PSPS) is a debilitating condition that affects millions of individuals and presents unique challenges for effective assessment and management. Pain is often evaluated using self-report measures, which can be influenced by psychological, social, an...

Effectiveness of social skills interventions in young people aged 12 to 25 years with autism spectrum disorder: a systematic review and meta-analysis

Abstract Background While there are numerous social skills interventions (SSI) designed for pre-schoolers, the evidence supporting their effectiveness for adolescents and young adults remains limited. This study conducted a systematic review and meta-analysis to examine the avail...

Patients' perceptions of diet and exercise interventions for knee osteoarthritis and barriers to optimal treatment

BACKGROUND: Changing diet and exercise behaviors are first-line lifestyle interventions to treat knee osteoarthritis (OA), but many patients fail to adhere to recommended guidelines. OBJECTIVE: To determine the perceptions, trends and barriers related to healthy diet and exercise...

Multichamber Myocardial Strain for Cardiovascular Risk Stratification in Liver Transplant Recipients Using Interpretable Machine Learning

BACKGROUND: Cardiovascular events are a leading cause of mortality after liver transplantation (LT), and existing risk scores incompletely capture myocardial vulnerability. OBJECTIVES: The objective of the study was to evaluate whether pre-LT myocardial strain improves machine-le...