SA Health

Understanding the Concept of Self‐Performed Ultrasound: A Scoping Review

Self-performed ultrasound is an emerging technology that facilitates adept self-scans in untrained hands. Inspired by self-performed imaging in space for more prompt diagnosis and therapy, it has the potential to accurately monitor chronic conditions remotely. However, the lack o...

Experience, influences, and impacts on breathlessness among people receiving care in the intensive care unit: A qualitative study

Introduction Breathlessness is frequently experienced by patients in the intensive care unit (ICU) and associated with anxiety and delays in weaning from mechanical ventilation. Breathlessness in this clinical setting remains under-recognised in clinical guidelines, and little is...

Identifying methodological guidance used for systematic reviews, clinical practice guidelines, and health technology assessment for rare diseases: a scoping review protocol.

OBJECTIVE: This scoping review will identify methodological guidance relevant to systematic reviews (SRs), clinical practice guidelines (CPGs), and health technology assessments (HTAs) for rare diseases, and examine methodological challenges associated with their development. INT...

Preparing for Future Group B Streptococcus Vaccines: Perspectives of Pregnant Women in Australia

Background: Vaccines for Group B Streptococcus (GBS) intended for pregnant women are currently in advanced stages of clinical trials. Conducting preparatory research now can help identify factors influencing GBS vaccine acceptance and potential challenges to future implementation...

Health workforce retention in remote Aboriginal and Torres Strait Islander communities in high-income countries: a rapid realist review

It is vital to reduce avoidable turnover and optimise retention of healthcare staff in Australian remote Aboriginal and Torres Strait Islander health services. However, evidence informing the implementation of retention interventions is limited as existing literature inadequately...

International Travel for Organ Transplantation: 2024 Multinational Survey of Routes, Organs, and Donor Types

BACKGROUND: International travel for organ transplantation (ITOT) reportedly affects ≥2% of global solid organ transplant activity, yet detailed information about ITOT participants, organ types, travel configurations, and clinical settings remains scarce. Previous research has fo...

Androgen drives early endosome vesicular trafficking machinery expression to alter Appl1 endosome and leptin signaling in prostate cancer

Prostate cancer is the most diagnosed cancer in men and remains a leading cause of cancer related mortality worldwide. A deeper understanding of the cellular and molecular mechanisms that drive prostate cancer progression is essential for improving patient management and identify...

The increasing burden of revision arthroplasty for infection and fracture: perspectives of a tertiary referral centre

Background: In public hospitals the number of complex urgent and semi-urgent revision joint replacements has increased over time, conversely the number of primary joint replacements has decreased. This study aimed to investigate the effect of this change on service delivery of el...

Mendelian randomisation and colocalisation reveal pleiotropic effects of the CD40/SLC12A5 locus on CD40 protein, depression, and immune disease

Abstract Inflammatory pathways are implicated in depression, but the specific immune proteins and causal variants involved remain unclear. This study investigated potential causal relationships between 91 immune-related plasma proteins and depression using generalized summary Men...