Russian Scientific Center of Surgery

Detection of Neutrophil Extracellular Traps by Flow Cytometry in Healthy Controls and Patients with Systemic Lupus Erythematosus

Excessive induction of neutrophil extracellular traps (NETs) formation (NETosis) and clearance system dysfunction lead to autoantigen accumulation, initiating autoimmune cascades in immune-mediated inflammatory rheumatic diseases. This study aims to quantitatively determine NETs...

A digital system for assessing psychoemotional stress, mental and cognitive abilities in personnel engaged in high-stress professional activities (medical staff)

Objective. To create a digital model of professional burnout syndrome (PBS) and dynamics of its main manifestations in healthcare workers undergoing combined physiotherapy. Material and methods. The study enrolled 50 healthcare workers (25 ones with PBS and 25 somatically healthy...

Surgical treatment of advanced age patients with bilateral carotid artery disease

Objective. To analyze the effectiveness of surgical treatment in elderly patients with bilateral atherosclerotic lesions of carotid arteries. Material and methods. Carotid endarterectomy was performed in 91 patients aged 75—90 years (62 men, 29 women; mean age 78±2 years) with bi...

Results of revascularization operations in geriatric patients with multifocal atherosclerosis

Background. Multifocal atherosclerosis (MFA) is one of the common diseases in elderly patients. Currently, there is no single approach to treating patients with MFA. The active implementation of endovascular surgery has significantly expanded the treatment options for comorbid el...

Resolution of the Expert Council “Non-steroidal anti-inflammatory drugs in the treatment of non-specific back pain and radiculopathy in the 2026 RASP guidelines”

In June 2025, an Expert Council of the Russian Association for the Study of Pain (RASP) was held. Specialists discussed the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of nonspecific (musculoskeletal) lower back pain. The meeting presented data from stu...

Machine Learning-Assisted SHG Morphometry Reveals Distinct Collagen Microarchitectures of Trabecular Bone and Fibrosis in Bone Marrow Biopsies

Abstract Collagen microarchitecture in bone marrow biopsies represents a largely underexplored source of quantitative biomarkers for histopathological diagnostics and analysis of tissue remodeling. While second harmonic generation (SHG) microscopy has been increasingly applied to...

SARIFA and Lipid Metabolic Reprogramming in Prostate Cancer: Fundamental Mechanisms, Tumor Microenvironment, and Novel Biomarker Prospects

Prostate cancer (PCa) is one of the most prevalent malignancies in men worldwide. Established clinicopathological parameters do not fully describe the biological heterogeneity of PCa or consistently predict its clinical course after radical prostatectomy, supporting the investiga...