Royal Victoria Hospital

The multifaceted role of the potassium channel KCNK1 in the early detection and prognostication of high-grade serous cancer

Abstract Background The sixth most common cancer in females in the UK, ovarian cancer remains a significant health burden due to its aggressive nature and stagnant mortality trends. The current gold standard biomarker, CA-125, has notable limitations, including low sensitivity in...

Incidence, Patterns and Predictors of Alemtuzumab‐Induced Thyroid Dysfunction in Patients With Multiple Sclerosis: A Northern Ireland Cohort Study

ABSTRACT Background Alemtuzumab (Lemtrada) is highly effective for selected relapsing multiple sclerosis (MS) but can cause autoimmune thyroid dysfunction (AITD). Our aim was to retrospectively review patients and the monitoring of their thyroid function tests (TFTs) during and a...